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Contrast media

In 1993, the world market for contrast media was already estimated to be worth $ 3 billion.

In 2001, an astonishing 12.2 million contrast medium-supported CT studies were carried out in Europe alone. Currently, the overall sales of contrast media are estimated to rise to $915 million in Europe in 2008.

In its brief history, two major developments occurred:
A switch from hyper- to low-osmolar iodinated agents (late 80s), after costs on the latter dropped
The widespread introduction of MRI contrast agents (90s), which largely accounts for the reduced market share of iodinated contrast media sales, from 91.7% in 1992 (world; non-ionic agents) to 60.7% est. (Europe) in 2008.

While many more compounds have been approved since – for use in the various imaging modalities – with the exception of the advent of ultrasound agents in Europe (1991) these are largely for use in specialist or research applications, e.g. intra-vascular (blood-pool) or tissue-specific (targeted) imaging.

This article was published on 05/01/2007

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